Proteomics PBC
Mapping Molecular Intelligence
Atlas of Biomarker Candidates (ABC)
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Updated
— Proteins
— Traits
23 Categories
Type to search across 1,072 biomarker entries — or browse by disease category below.
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Protein Interaction Network

Interaction data from STRING-DB (v12, human). 537 atlas proteins · 5,373 interactions. Node size = diseases implicated. Color = primary disease category.

0.70
Building network…
Apr 2026
v2.2 — DDC annotation (with caveats)
  • +1 entry: DOPA Decarboxylase (DDC) added to Parkinson’s Disease with critical treatment caveat
  • Plasma DDC elevated in treated PD only — NOT in de novo/untreated patients (p=0.128–0.233)
  • Bolsewig et al. 2025 (Nat Commun, N=1,635); Pereira et al. 2023 (Nat Aging)
  • Total: 1,072 entries; 78 proteins in PD category
Apr 2026
v2.1 — Literature expansion (9 papers)
  • +60 new biomarker entries; +41 new gene symbols (692 → 748 unique proteins)
  • Parkinson’s Disease: 11 proteins — Homann et al. 2025 (SomaScan-7K, N=74,000)
  • Colorectal Cancer: 15 proteins — Sun et al. 2024 (Olink, UKB N=52,231)
  • Type 2 Diabetes: 9 proteins — Ngo et al. 2021 & Huth et al. 2018
  • Heart Failure: 7 proteins — Emilsson et al. 2024 (SomaScan V3-5K, N=5,457)
  • Brain/Organ Aging: 7 proteins — Lehallier et al. 2023 (SomaScan v4, N=5,676)
  • Acute MI & CVD: 9 proteins — Beck et al. 2024 & Lassé et al. 2021
  • Depression: 2 proteins — Zhang et al. 2025 (Olink, N=412)
  • 7 existing entries updated with replication notes (ADIPOQ, SHBG, HPGDS, NPPB, TNNT2, COL9A1, CRTAC1)
Early 2026
v2.0 — Atlas launch
  • 1,011 entries across 22 disease categories; 692 unique proteins
  • Protein Interaction Network, Strategic Assessment, Nomic panel filter
  • Disease-specific and pleiotropic protein views